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William E. Barlow, PhD
Senior Investigator

Research Interests:
Dr. Barlow is a biostatistician with interests in outcomes of breast cancer screening and treatment.

Contact Dr. Barlow:
Voice Mail: 206-287-2936
E-Mail: barlow.w@ghc.org

Recent Publications:
Billingsley KG, Morris AM, Green P, Dominitz JA, Matthews B, Dobie SA, Barlow W, Baldwin LM. Does surgeon case volume influence nonfatal adverse outcomes after rectal cancer resection? J Am Coll Surg. 2008;206(6):1167-77. Epub 2008 Apr 14. Abstract

Cherkin DC, Sherman KJ, Hogeboom CJ, Erro JH, Barlow WE, Deyo RA, Avins AL. Efficacy of acupuncture for chronic low back pain: protocol for a randomized controlled trial. Trials. 2008;9(1):10. Abstract

Dunnwald LK, Gralow JR, Ellis GK, Livingston RB, Linden HM, Specht JM, Doot RK, Lawton TJ, Barlow WE, Kurland BF, Schubert EK, Mankoff DA. Tumor metabolism and blood flow changes by positron emission tomography: relation to survival in patients treated with neoadjuvant chemotherapy for locally advanced breast cancer. J Clin Oncol. 2008 Jul 14. [Epub ahead of print]. Abstract

Jackson ML, Nelson JC, Weiss NS, Neuzil KM, Barlow W, Jackson LA. Influenza vaccination and risk of community-acquired pneumonia in immunocompetent elderly people: a population-based, nested case-control study. Lancet. 2008 Aug 2;372(9636):398-405. Abstract

Taplin S, Abraham L, Barlow WE, Fenton JJ, Berns EA, Carney PA, Cutter GR, Sickles EA, Carl D, Elmore JG. Mammography facility characteristics associated with interpretive accuracy of screening mammography. J Natl Cancer Inst. 2008;100(12):876-87. Epub 2008 Jun 10. Abstract

Tice JA, Cummings SR, Smith-Bindman R, Ichikawa L, Barlow WE, Kerlikowske K. Using clinical factors and mammographic breast density to estimate breast cancer risk: development and validation of a new predictive model. Ann Intern Med. 2008;148(5):337-47. Abstract

2007
Billingsley KG, Morris AM, Dominitz JA, Matthews B, Dobie S, Barlow W, Wright GE, Baldwin LM. Surgeon and hospital characteristics as predictors of major adverse outcomes following colon cancer surgery: understanding the volume-outcome relationship. Arch Surg. 2007;142(1):23-31; discussion 32. Abstract

Fenton JJ, Rolnick SJ, Harris EL, Barton MB, Barlow WE, Reisch LM, Herrinton LJ, Geiger AM, Fletcher SW, Elmore JG. Specificity of clinical breast examination in community practice. J Gen Intern Med. 2007;22(3):332-7. Abstract

Fenton JJ, Taplin SH, Carney PA, Abraham L, Sickles EA, D'Orsi C, Berns EA, Cutter G, Hendrick RE, Barlow WE, Elmore JG. Influence of computer-aided detection on performance of screening mammography. New Engl J Med. 2007; 356(14):1399-1409. Abstract

Hudis CA, Barlow WE, Costantino JP, Gray RJ, Pritchard KI, Chapman JA, Sparano JA, Hunsberger S, Enos RA, Gelber RD, Zujewski JA. Proposal for standardized definitions for efficacy end points in adjuvant breast cancer trials: the STEEP system. J Clin Oncol. 2007;25(15):2127-32. Abstract

Mankoff DA, O'Sullivan F, Barlow WE, Krohn KA. Molecular imaging research in the outcomes era measuring outcomes for individualized cancer therapy. Acad Radiol. 2007;14(4):398-405. Details

Moore HC, Green SJ, Gralow JR, Bearman SI, Lew D, Barlow WE, Hudis C, Wolff AC, Ingle JN, Chew HK, Elias AD, Livingston RB, Martino S. Intensive dose-dense compared with high-dose adjuvant chemotherapy for high-risk operable breast cancer: Southwest Oncology Group/Intergroup study 9623. J Clin Oncol. 2007;25(13):1677-82. Epub 2007 Apr 2. Abstract

Morris AM, Baldwin LM, Matthews B, Dominitz JA, Barlow WE, Dobie SA, Billingsley KG. Reoperation as a quality indicator in colorectal surgery: a population-based analysis. Ann Surg. 2007;245(1):73-9. Abstract

Schell MJ, Yankaskas BC, Ballard-Barbash R, Qaqish BF, Barlow WE, Rosenberg RD, Smith-Bindman R. Evidence-based target recall rates for screening mammography. Radiology. 2007;243(3):681-9. Abstract

Wright GE, Barlow WE, Green P, Baldwin LM, Taplin SH. Differences among the elderly in the treatment costs of colorectal cancer: how important is race? Med Care. 2007;45(5):420-30. Abstract

2006
Baldwin LM, Klabunde CN, Green P, Barlow W, Wright G. In search of the perfect comorbidity measure for use with administrative claims data: does it exist? Med Care. 2006;44(8):745-53. Abstract

Barlow WE, White E, Ballard-Barbash R, Vacek PM, Titus-Ernstoff L, Carney PA, Tice JA, Buist DS, Geller BM, Rosenberg R, Yankaskas BC, Kerlikowske K. Prospective breast cancer risk prediction model for women undergoing screening mammography. J Natl Cancer Inst. 2006;98(17):1204-14. Abstract

Dobie SA, Baldwin LM, Dominitz JA, Matthews B, Billingsley K, Barlow W. Completion of therapy by Medicare patients with stage III colon cancer. J Natl Cancer Inst. 2006;98(9):610-9. Abstract

Fenton JJ, Egger J, Carney PA, Cutter G, D'Orsi C, Sickles EA, Fosse J, Abraham L, Taplin SH, Barlow W, Hendrick RE, Elmore JG. Reality check: perceived versus actual performance of community mammographers. AJR Am J Roentgenol. 2006;187(1):42-6. Abstract

Geller BM, Ichikawa LE, Buist DS, Sickles EA, Carney PA, Yankaskas BC, Dignan M, Kerlikowske K, Yabroff KR, Barlow W, Rosenberg RD. Improving the concordance of mammography assessment and management recommendations. Radiology. 2006;241(1):67-75. Abstract

Paliwal P, Gelfand AE, Abraham L, Barlow W, Elmore JG. Examining accuracy of screening mammography using an event order model. Stat Med. 2006;25(2):267-83. Abstract

Porter PL, Barlow WE, Yeh IT, Lin MG, Yuan XP, Donato E, Sledge GW, Shapiro CL, Ingle JN, Haskell CM, Albain KS, Roberts JM, Livingston RB, Hayes DF. p27(Kip1) and cyclin E expression and breast cancer survival after treatment with adjuvant chemotherapy. J Natl Cancer Inst. 2006;98(23):1723-31. Abstract

Rosenberg RD, Yankaskas BC, Abraham LA, Sickles EA, Lehman CD, Geller BM, Carney PA, Kerlikowske K, Buist DS, Weaver DL, Barlow WE, Ballard-Barbash R. Performance benchmarks for screening mammography. Radiology. 2006;241(1):55-66. Abstract

Smith-Bindman R, Miglioretti DL, Lurie N, Abraham L, Barbash RB, Strzelczyk J, Dignan M, Barlow WE, Beasley CM, Kerlikowske K. Does utilization of screening mammography explain racial and ethnic differences in breast cancer? Ann Intern Med. 2006;144(8):541-53. Abstract

Weaver DL, Rosenberg RD, Barlow WE, Ichikawa L, Carney PA, Kerlikowske K, Buist DS, Geller BM, Key CR, Maygarden SJ, Ballard-Barbash R. Pathologic findings from the breast cancer surveillance consortium. Cancer. 2006;106(4):732-42. Epub 2006 Jan 12. Abstract

2005

Baldwin LM, Dobie SA, Billingsley K, Cai Y, Wright GE, Dominitz JA, Barlow W, Warren JL, Taplin SH. Explaining black-white differences in receipt of recommended colon cancer treatment. J Natl Cancer Inst. 2005;97(16):1211-20. Abstract

D'Orsi C, Tu SP, Nakano C, Carney PA, Abraham LA, Taplin SH, Hendrick RE, Cutter GR, Berns E, Barlow WE, Elmore JG. Current realities of delivering mammography services in the community: Do challenges with staffing and scheduling exist? Radiology. 2005;235(2):391-5. Epub 2005 Mar 29. Abstract

Dunnwald LK, Gralow JR, Ellis GK, Livingston RB, Linden HM, Lawton TJ, Barlow WE, Schubert EK, Mankoff DA. Residual tumor uptake of [(99m)Tc]-sestamibi after neoadjuvant chemotherapy for locally advanced breast carcinoma predicts survival. Cancer. 2005;103:680-88. Abstract

Egger JR, Cutter GR, Carney PA, Taplin SH, Barlow WE, Hendrick RE, D'Orsi CJ, Fosse JS, Abraham L, Elmore JG. Mammographers' perception of women's breast cancer risk. Med Decis Making. 2005;25(3):283-9. Abstract

Elmore JG, Reisch LM, Barton MB, Barlow WE, Rolnick S, Harris EL, Herrinton LJ, Geiger AM, Beverly RK, Hart G, Yu O, Greene SM, Weiss NS, Fletcher SW. Efficacy of breast cancer screening in the community according to risk level. J Natl Cancer Inst. 2005;97(14):1035-43. Abstract

Elmore JG, Taplin SH, Barlow WE, Cutter GR, D'Orsi CJ, Hendrick RE, Abraham LA, Fosse JS, Carney PA. Does litigation influence medical practice? The influence of community radiologists' medical malpractice perceptions and experience on screening mammography. Radiology. 2005;236(1):37-46. Abstract

Fenton JJ, Barton MB, Geiger AM, Herrinton LJ, Rolnick SJ, Harris EL, Barlow WE, Reisch LM, Fletcher SW, Elmore JG. Screening clinical breast examination: how often does it miss lethal breast cancer? J Natl Cancer Inst Monogr. 2005;(35):67-71.

Geiger AM, Yu O, Herrinton LJ, Barlow WE, Harris EL, Rolnick S, Barton MB, Elmore JG, Fletcher SW. A population-based study of bilateral prophylactic mastectomy efficacy in women at elevated risk for breast cancer in community practices. Arch Intern Med. 2005;165(5):516-20. Abstract

Hendrick RE, Cutter GR, Berns EA, Nakano C, Egger J, Carney PA, Abraham L, Taplin SH, D'Orsi CJ, Barlow W, Elmore JG. Community-based mammography practice: services, charges, and interpretation methods. AJR Am J Roentgenol. 2005;184(2):433-8. Abstract

Herrinton LJ, Barlow WE, Yu O, Geiger AM, Elmore JG, Barton MB, Harris EL, Rolnick S, Pardee R, Husson G, Macedo A, Fletcher SW. Efficacy of prophylactic mastectomy in women with unilateral breast cancer. J Clin Oncol. 2005;23(19):4275-86. Epub 2005 Mar 28. Abstract

Kerlikowske K, Smith-Bindman R, Abraham LA, Lehman CD, Yankaskas BC, Ballard-Barbash R, Barlow WE, Voeks JH, Geller BM, Carney PA, Sickles EA. Breast cancer yield for screening mammographic examinations with recommendation for short-interval follow-up. Radiology. 2005;234(3):684-92.  Abstract

Mouchawar J, Taplin S, Ichikawa L, Barlow WE, Geiger AM, Weinmann S, Gilbert J, Manos MM, Yood MU. Late stage breast cancer among women with recent negative screening mammography: do clinical encounters offer opportunity for earlier detection? J Natl Cancer Inst Monogr. 2005;35:39-45.

Scholes D, LaCroix AZ, Ichikawa LE, Barlow WE, Ott SM. Change in bone mineral density among adolescent women using and discontinuing depot medroxyprogesterone acetate contraception. Arch Pediatr Adolesc. Med 2005;159(2):139-44. Abstract

Taplin SH, Barlow WE, Ulcickas-Yood M, Westbrook E, Geiger AM, Bischoff K, Ichikawa L. Re: Breast cancer screening comes full circle (letter). J Natl Cancer Inst. 2005;97(6):461. Details

Weinmann S, Taplin SH, Gilbert J, Beverly RK, Geiger AM, Yood MU, Mouchawar J, Manos MM, Zapka JG, Westbrook E, Barlow WE. Characteristics of women refusing follow-up for tests or symptoms suggestive of breast cancer. J Natl Cancer Inst Monogr. 2005;(35):33-8.

Yankaskas BC, Taplin SH, Ichikawa L, Geller BM, Rosenberg RD, Carney PA, Kerlikowske K, Ballard-Barbash R, Cutter GR, Barlow WE. Association between mammography timing and measures of screening performance in the United States. Radiology. 2005;234(2):363-73. Abstract

Zheng Y, Barlow WE, Cutter G. Assessing accuracy of mammography in the presence of verification bias and intrareader correlation. Biometrics. 2005;61(1):259-68. Abstract

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  • Flu vaccine may not protect seniors well; Group Health study in Lancet finds no less risk of pneumonia with vaccine. See news release.

 

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