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Bruce M. Psaty, MD, PhD
Senior Investigator

Research Interests:

Dr. Psaty is a general internist and cardiovascular disease epidemiologist with interests and expertise in pharmacoepidemiology, pharmacogenetics, and drug safety. Also a professor of medicine, epidemiology, and health services at the University of Washington (UW), he co-directs the UW's Cardiovascular Health Research Unit.

Psaty's work includes population-based case-control studies of myocardial infarction, stroke, and venous thromboembolism conducted at Group Health Cooperative. His primary research interests include the study of drug treatment for high blood pressure, hormone replacement therapy in postmenopausal women, and new or emerging risk factors for heart disease and stroke. 

His several current NIH-funded projects focus on interactions between medications and genes; they represent efforts to translate findings from the Human Genome Project into clinical practice and, thus, improve the safety and efficacy of commonly used medications. He helps design and conduct multi-center cohort studies, including the Cardiovascular Health Study and the Multi-Ethnic Study of Atherosclerosis, funded by the National Heart, Lung, and Blood Institute. He also teaches and mentors students, fellows, and junior faculty in medicine and epidemiology.

A national leader in encouraging better post-market surveillance of Food and Drug Administration-approved medications, Dr. Psaty is a member of an Institute of Medicine panel charged with reviewing drug safety methods and policies for the United States. He also serves as chair of Group Health Cooperative's Research Committee and chair of the NIH Cardiovascular Disease and Sleep Study Section.

Psaty maintains a small but long-standing primary care practice in the Adult Medicine Clinic at Harborview Medical Center.

Contact Dr. Psaty:
Voice Mail: 206-287-2777, CHRU 
E-Mail: psaty@u.washington.edu

Recent Publications:
Enquobahrie DA, Smith NL, Bis JC, Carty CL, Rice KM, Lumley T, Hindorff LA, Lemaitre RN, Williams MA, Siscovick DS, Heckbert SR, Psaty BM. Cholesterol ester transfer protein, interleukin-8, peroxisome proliferator activator receptor alpha, and toll-like receptor 4 genetic variations and risk of incident nonfatal myocardial infarction and ischemic stroke. Am J Cardiol. 2008 Jun 15;101(12):1683-8. Epub 2008 Apr 9. Abstract

Fornage M, Chiang YA, O'Meara ES, Psaty BM, Reiner AP, Siscovick DS, Tracy RP, Longstreth WT Jr. Biomarkers of inflammation and MRI-defined small vessel disease of the brain. The Cardiovascular Health Study. Stroke. 2008; [Epub ahead of print]. Abstract

Heckbert SR, Li G, Cummings SR, Smith NL, Psaty BM. Use of alendronate and risk of incident atrial fibrillation in women. Arch Intern Med. 2008;168(8):826-31. Abstract

Hindorff LA, Lemaitre RN, Smith NL, Bis JC, Marciante KD, Rice KM, Lumley T, Enquobahrie DA, Li G, Heckbert SR, Psaty BM. Common genetic variation in six lipid-related and statin-related genes, statin use and risk of incident nonfatal myocardial infarction and stroke. Pharmacogenet Genomics. 2008 Aug;18(8):677-682. Abstract

Kaplan RC, McGinn AP, Pollak MN, Kuller L, Strickler HD, Rohan TE, Cappola AR, Xue X, Psaty BM. High insulinlike growth factor binding protein 1 level predicts incident congestive heart failure in the elderly. Am Heart J. 2008;155(6):1006-12. Epub 2008 Mar 5. Abstract

Kaplan RC, McGinn AP, Pollak MN, Kuller L, Strickler HD, Rohan TE, Xue X, Kritchevsky SB, Newman AB, Psaty BM. Total insulinlike growth factor 1 and insulinlike growth factor binding protein levels, functional status, and mortality in older adults. J Am Geriatr Soc. 2008;56(4):652-60. Epub 2008 Feb 27. Abstract

Kaplan RC, Smith NL, Zucker S, Heckbert SR, Rice K, Psaty BM. Matrix metalloproteinase-3 (MMP3) and MMP9 genes and risk of myocardial infarction, ischemic stroke, and hemorrhagic stroke. Atherosclerosis. 2008 Mar 12; [Epub ahead of print]. Abstract

Lemaitre RN, Heckbert SR, Sotoodehnia N, Bis JC, Smith NL, Marciante KD, Hindorff LA, Lange LA, Lumley TS, Rice KM, Wiggins KL, Psaty BM. Beta1- and beta2-adrenergic receptor gene variation, beta-blocker use and risk of myocardial infarction and stroke. Am J Hypertens. 2008;21(3):290-6. Epub 2008 Jan 24. Abstract

Lovasi GS, Moudon AV, Pearson AL, Hurvitz PM, Larson EB, Siscovick DS, Berke EM, Lumley T, Psaty BM. Using built environment characteristics to predict walking for exercise. Int J Health Geogr. 2008;7(1):10. Abstract

Lumley T, Rice KM, Psaty BM. Carryover effects after cessation of drug treatment: trophies or dreams? Am J Hypertens. 2008;21(1):14-6. Abstract

McGinn AP, Kaplan RC, Verghese J, Rosenbaum DM, Psaty BM, Baird AE, Lynch JK, Wolf PA, Kooperberg C, Larson JC, Wassertheil-Smoller S. Walking speed and risk of incident ischemic stroke among postmenopausal women. Stroke. 2008;39(4):1233-9. Epub 2008 Feb 21. Abstract

Mittalhenkle A, Stehman-Breen CO, Shlipak MG, Fried LF, Katz R, Young BA, Seliger S, Gillen D, Newman AB, Psaty BM, Siscovick D. Cardiovascular risk factors and incident acute renal failure in older adults: the cardiovascular health study. Clin J Am Soc Nephrol. 2008;3(2):450-6. Epub 2008 Feb 6. Abstract

Moran A, Katz R, Smith NL, Fried LF, Sarnak MJ, Seliger SL, Psaty B, Siscovick DS, Gottdiener JS, Shlipak MG. Cystatin C concentration as a predictor of systolic and diastolic heart failure. J Card Fail. 2008;14(1):19-26. Abstract

Psaty BM. Potential revisions to hypertension guidelines. Am J Hypertens. 2008;21(2):134-135. Details

Psaty BM, Kronmal RA. Reporting mortality findings in trials of rofecoxib for Alzheimer disease or cognitive impairment: a case study based on documents from rofecoxib litigation. JAMA. 2008;299(15):1813-7. Abstract

Psaty BM, Lumley T. Surrogate end points and FDA approval: a tale of 2 lipid-altering drugs. JAMA. 2008;299(12):1474-6. Details

Psaty BM, Ray W. FDA guidance on off-label promotion and the state of the literature from sponsors. JAMA. 2008;299(16):1949-51. Details

van Stralen KJ, Doggen CJ, Lumley T, Cushman M, Folsom AR, Psaty BM, Siscovick D, Rosendaal FR, Heckbert SR. The relationship between exercise and risk of venous thrombosis in elderly people. J Am Geriatr Soc. 2008;56(3):517-22. Epub 2008 Jan 4. Abstract

Weiss NS, Koepsell TD, Psaty BM. Generalizability of the results of randomized trials. Arch Intern Med. 2008;168(2):133-5. Details

2007
Ballantyne C, Cushman M, Psaty B, Furberg C, Khaw KT, Sandhu M, Oldgren J, Rossi GP, Maiolino G, Cesari M, Lenzini L, James SK, Rimm E, Collins R, Anderson J, Koenig W, Brenner H, Rothenbacher D, Berglund G, Persson M, Berger P, Brilakis E, McConnell JP, Koenig W, Sacco R, Elkind M, Talmud P, Rimm E, Cannon CP, Packard C, Barrett-Connor E, Hofman A, Kardys I, Witteman JC, Criqui M, Corsetti JP, Rainwater DL, Moss AJ, Robins S, Bloomfield H, Collins D, Packard C, Wassertheil-Smoller S, Ridker P, Ballantyne C, Cannon CP, Cushman M, Danesh J, Gu D, Hofman A, Nelson JJ, Thompson S, Zalewski A, Zariffa N, Di Angelantonio E, Kaptoge S, Thompson A, Thompson S, Walker M, Watson S, Wood A. Collaborative meta-analysis of individual participant data from observational studies of Lp-PLA2 and cardiovascular diseases. Eur J Cardiovasc Prev Rehabil. 2007;14(1):3-11. Abstract

Bis JC, Heckbert SR, Smith NL, Reiner AP, Rice K, Lumley T, Hindorff LA, Marciante KD, Enquobahrie DA, Monks SA, Psaty BM. Variation in inflammation-related genes and risk of incident nonfatal myocardial infarction or ischemic stroke. Atherosclerosis. 2008;198(1):166-73. Epub 2007 Nov 5. Abstract

Burke W, Psaty BM. Personalized medicine in the era of genomics. JAMA. 2007;298(14):1682-4. Details

Cao JJ, Arnold AM, Manolio TA, Polak JF, Psaty BM, Hirsch CH, Kuller LH, Cushman M. Association of carotid artery intima-media thickness, plaques, and c-reactive protein with future cardiovascular disease and all-cause mortality. The Cardiovascular Health Study. Circulation. 2007;116(1):32-8. Epub 2007 Jun 18. Abstract

Cao JJ, Biggs ML, Barzilay J, Konen J, Psaty BM, Kuller L, Bleyer AJ, Olson J, Wexler J, Summerson J, Cushman M. Cardiovascular and mortality risk prediction and stratification using urinary albumin excretion in older adults ages 68-102: the Cardiovascular Health Study. Atherosclerosis. 2008;197(2):806-13. Epub 2007 Sep 17. Abstract

Glazer NL, Dublin S, Smith NL, French B, Jackson LA, Hrachovec JB, Siscovick DS, Psaty BM, Heckbert SR. Newly detected atrial fibrillation and compliance with antithrombotic guidelines. Arch Intern Med. 2007;167(3):246-52. Abstract

Hindorff LA, Heckbert SR, Smith N, Marciante KD, Psaty BM. Common VKORC1 variants are not associated with arterial or venous thrombosis. J Thromb Haemost. 2007;5(10):2025-7. Abstract

Hindorff LA, Rice KM, Lange LA, Diehr P, Halder I, Walston J, Kwok P, Ziv E, Nievergelt C, Cummings SR, Newman AB, Tracy RP, Psaty BM, Reiner AP. Common variants in the CRP gene in relation to longevity and cause-specific mortality in older adults: the Cardiovascular Health Study. Atherosclerosis. 2007; [Epub ahead of print]. Abstract

Jenny NS, Yanez ND, Psaty BM, Kuller LH, Hirsch CH, Tracy RP. Inflammation biomarkers and near-term death in older men. Am J Epidemiol. 2007;165(6):684-95. Epub 2007 Jan 10. Abstract

Kaplan RC, McGinn AP, Pollak MN, Kuller LH, Strickler HD, Rohan TE, Cappola AR, Xue X, Psaty BM. Association of total IGF-I, IGFBP-1 and IGFBP-3 levels with incident coronary events and ischemic stroke. J Clin Endocrinol Metab. 2007;92(4):1319-25. Epub 2007 Jan 30. Abstract

Lovasi GS, Lemaitre RN, Siscovick DS, Dublin S, Bis JC, Lumley T, Heckbert SR, Smith NL, Psaty BM. Amount of leisure-time physical activity and risk of nonfatal myocardial infarction. Ann Epidemiol. 2007;17(6):410-6. Epub 2007 Feb 23. Abstract

Lovasi GS, Moudon AV, Smith NL, Lumley T, Larson EB, Sohn DW, Siscovick DS, Psaty BM. Evaluating options for measurement of neighborhood socioeconomic context: evidence from a myocardial infarction case-control study. Health Place. 2008;14(3):453-67. Epub 2007 Sep 21. Abstract

Lovasi GS, Weiss JC, Hoskins R, Whitsel EA, Rice K, Erickson CF, Psaty BM. Comparing a single-stage geocoding method to a multi-stage geocoding method: how much and where do they disagree? Int J Health Geogr. 2007;6:12. Abstract

Marciante KD, Bis JC, Rieder MJ, Reiner AP, Lumley T, Monks SA, Kooperberg C, Carlson C, Heckbert SR, Psaty BM. Renin-angiotensin system haplotypes and the risk of myocardial infarction and stroke in pharmacologically treated hypertensive patients. Am J Epidemiol. 2007;166(1):19-27. Epub 2007 May 22. Abstract

Mukamal KJ, Psaty BM, Rautaharju PM, Furberg CD, Kuller LH, Mittleman MA, Gottdiener JS, Siscovick DS. Alcohol consumption and risk and prognosis of atrial fibrillation among older adults: the Cardiovascular Health Study. Am Heart J. 2007;153(2):260-6. Abstract

Novaro GM, Katz R, Aviles RJ, Gottdiener JS, Cushman M, Psaty BM, Otto CM, Griffin BP. Clinical factors, but not C-reactive protein, predict progression of calcific aortic-valve disease: the Cardiovascular Health Study. J Am Coll Cardiol. 2007;50(20):1992-8. Epub 2007 Oct 29. Abstract

Palmas W, Ma S, Psaty B, Goff DC Jr, Darwin C, Barr RG. Antihypertensive medications and C-reactive protein in the multi-ethnic study of atherosclerosis. Am J Hypertens. 2007;20(3):233-41. Abstract

Psaty B. Heart-stopping news. The diabetes drug Avandia is under fire: what you should know. Interview by Avery Comarow. US News World Rep. 2007;142(20):64. Details

Psaty BM, Arnett D, Burke G. A new era of cardiovascular disease epidemiology. JAMA. 2007;298(17):2060-2. Details

Psaty BM, Charo RA. FDA responds to Institute of Medicine drug safety recommendations--in part. JAMA. 2007;297(17):1917-20. Details

Psaty BM, Furberg CD. The record on rosiglitazone and the risk of myocardial infarction. N Engl J Med. 2007;357(1):67-9. Epub 2007 Jun 5. Details

Psaty BM, Korn D. Congress responds to the IOM drug safety report--in full. JAMA. 2007;298(18):2185-7. Details

Psaty BM, Weiss NS. NSAID trials and the choice of comparators--questions of public health importance. N Engl J Med. 2007;356(4):328-30. Abstract

Rajpathak SN, McGinn AP, Strickler HD, Rohan TE, Pollak M, Cappola AR, Kuller L, Xue X, Newman AB, Strotmeyer ES, Psaty BM, Kaplan RC. Insulin-like growth factor-(IGF)-axis, inflammation, and glucose intolerance among older adults. Growth Horm IGF Res. 2008;18(2):166-73. Epub 2007 Sep 27. Abstract

Shiffman D, O'Meara ES, Bare LA, Rowland CM, Louie JZ, Arellano AR, Lumley T, Rice K, Iakoubova O, Luke MM, Young BA, Malloy MJ, Kane JP, Ellis SG, Tracy RP, Devlin JJ, Psaty BM. Association of gene variants with incident myocardial infarction in the Cardiovascular Health Study. Arterioscler Thromb Vasc Biol. 2007; [Epub ahead of print]. Abstract

Smith NL, Bis JC, Biagiotti S, Rice K, Lumley T, Kooperberg C, Wiggins KL, Heckbert SR, Psaty BM. Variation in 24 hemostatic genes and associations with non-fatal myocardial infarction and ischemic stroke. J Thromb Haemost. 2008;6(1):45-53. Epub 2007 Oct 10. Abstract

Smith NL, Hindorff LA, Heckbert SR, Lemaitre RN, Marciante KD, Rice K, Lumley T, Bis JC, Wiggins KL, Rosendaal FR, Psaty BM. Association of genetic variations with nonfatal venous thrombosis in postmenopausal women. JAMA. 2007;297(5):489-98. Abstract

Szekely CA, Breitner JC, Fitzpatrick AL, Rea TD, Psaty BM, Kuller LH, Zandi PP. NSAID use and dementia risk in the Cardiovascular Health Study. Role of APOE and NSAID type. Neurology. 2007;70(1):17-24. Epub 2007 Nov 14. Abstract

Walston JD, Fallin MD, Cushman M, Lange L, Psaty B, Jenny N, Browner W, Tracy R, Durda P, Reiner A. IL-6 gene variation is associated with IL-6 and C-reactive protein levels but not cardiovascular outcomes in the Cardiovascular Health Study. Hum Genet. 2007;22(5):485-94. Epub 2007 Sep 13. Abstract

Zakai NA, Katz R, Jenny NS, Psaty BM, Reiner AP, Schwartz SM, Cushman M. Inflammation and hemostasis biomarkers and cardiovascular risk in the elderly: the cardiovascular health study. J Thromb Haemost. 2007;5(6):1128-35. Epub 2007 Mar 21. Abstract

2006
Dublin S, French B, Glazer NL, Wiggins KL, Lumley T, Psaty BM, Smith NL, Heckbert SR. Risk of new-onset atrial fibrillation in relation to body mass index. Arch Intern Med. 2006;166(21):2322-8. Abstract

Fitzpatrick AL, Kronmal RA, Gardner JP, Psaty BM, Jenny NS, Tracy RP, Walston J, Kimura M, Aviv A. Leukocyte telomere length and cardiovascular disease in the Cardiovascular Health Study. Am J Epidemiol. 2007;165(1):14-21. Epub 2006 Oct 16. Abstract

French B, Lumley T, Monks SA, Rice KM, Hindorff LA, Reiner AP, Psaty BM Simple estimates of haplotype relative risks in case-control data. Genet Epidemiol. 2006;30(6):485-94. Abstract

Goff DC Jr, Bertoni AG, Kramer H, Bonds D, Blumenthal RS, Tsai MY, Psaty BM. Dyslipidemia prevalence, treatment, and control in the Multi-Ethnic Study of Atherosclerosis (MESA): gender, ethnicity, and coronary artery calcium. Circulation. 2006;113(5):647-56. Abstract

Heffelfinger JD, Heckbert SR, Psaty BM, Weiss NS, Thompson WW, Bridges CB, Jackson LA. Influenza vaccination and risk of incident myocardial infarction. Hum Vaccin. 2006;2(4):161-6. Epub 2006 Jul 24. Abstract

Hindorff LA, Psaty BM, Carlson CS, Heckbert SR, Lumley T, Smith NL, Lemaitre RN, Rieder MJ, Nickerson DA, Reiner AP. Common genetic variation in the prothrombin gene, hormone therapy, and incident nonfatal myocardial infarction in postmenopausal women. Am J Epidemiol. 2006;163(7):600-7. Epub 2006 Feb 8. Abstract

Jenny NS, Arnold AM, Kuller LH, Sharrett AR, Fried LP, Psaty BM, Tracy RP. Soluable intracellular adhesion molecule-1 is associated with cardiovascular disease risk and mortality in older adults. J Thromb Haemost. 2006;4(1):107-11. Abstract

Jenny NS, Arnold AM, Kuller LH, Tracy RP, Psaty BM. Serum amyloid p and cardiovascular disease in older men and women. results from the Cardiovascular Health Study. Arterioscler Thromb Vasc Biol. 2007;27(2):352-8. Epub 2006 Nov 30. Abstract

Kaplan RC, Tirschwell DL, Longstreth WT Jr, Manolio TA, Heckbert SR, LeValley AJ, Lefkowitz D, El-Saed A, Psaty BM. Blood pressure level and outcomes in adults aged 65 and older with prior ischemic stroke. J Am Geriatr Soc. 2006;54(9):1309-16. Abstract

Kooperberg C, Bis JC, Marciante K, Heckbert SR, Lumley T, Psaty BM. Logic regression for analysis of the association between genetic variation in the renin-angiotensin system and myocardial infarction or stroke. Am J Epidemiol. 2007;165(3):334-43. Epub 2006 Nov 2. Abstract

Kronmal RA, Barzilay JI, Smith NL, Psaty BM, Kuller LH, Burke GL, Furberg C. Mortality in pharmacologically treated older adults with diabetes: the Cardiovascular Health Study, 1989-2001. PLoS Med. 2006;3(10):e400. Abstract

Kuller LH, Arnold AM, Psaty BM, Robbins JA, O’Leary DH, Tracy RP, Burke GL, Manolio TA, Chaves PH. 10-year follow-up of subclinical cardiovascular disease and risk of coronary heart disease in the Cardiovascular Health Study. Arch Intern Med. 2006;166(1):71-8. Abstract

Lange LA, Carlson CS, Hindorff LA, Lange EM, Walston J, Durda JP, Cushman M, Bis JC, Zeng D, Lin D, Kuller LH, Nickerson DA, Psaty BM, Tracy RP, Reiner AP. Association of polymorphisms in the CRP gene with circulating C-reactive protein levels and cardiovascular events. JAMA. 2006;296(22):2703-11. Abstract

Lemaitre RN, Weiss NS, Smith NL, Psaty BM, Lumley T, Larson EB, Heckbert SR. Esterified estrogen and conjugated equine estrogen and the risk of incident myocardial infarction and stroke. Arch Intern Med. 2006;166(4):399-404. Abstract

Mora S, Szklo M, Otvos JD, Greenland P, Psaty BM, Goff DC Jr, O'leary DH, Saad MF, Tsai MY, Sharrett AR. LDL particle subclasses, LDL particle size, and carotid atherosclerosis in the Multi-Ethnic Study of Atherosclerosis (MESA). Atherosclerosis. 2006;192(1):211-7. Epub 2006 Jun 9. Abstract

Mukamal KJ, Chung H, Jenny NS, Kuller LH, Longstreth WT Jr, Mittleman MA, Burke GL, Cushman M, Psaty BM, Siscovick DS. Alcohol consumption and risk of coronary heart disease in older adults: the cardiovascular health study. J Am Geriatr Soc. 2006;54(1):30-7. Abstract

Pearte CA, Furberg CD, O'Meara ES, Psaty BM, Kuller L, Powe NR, Manolio T. Characteristics and baseline clinical predictors of future fatal versus nonfatal coronary heart disease events in older adults: the Cardiovascular Health Study. Circulation. 2006;113(18):2177-85.Epub 2006 May 1. Abstract

Peralta CA, Ziv E, Katz R, Reiner A, Burchard EG, Fried L, Kwok PY, Psaty B, Shlipak M. African ancestry, socioeconomic status, and kidney function in elderly African Americans: a genetic admixture analysis. J Am Soc Nephrol. 2006;17(12):3491-6. Epub 2006 Nov 2. Abstract

Psaty BM, Arnold AM, Olson J, Saad MF, Shea S, Post W, Burke GL. Association between levels of blood pressure and measures of subclinical disease multi-ethnic study of atherosclerosis. Am J Hypertens. 2006;19(11):1110-7. Abstract

Psaty BM, Burke SP. Protecting the health of the public--Institute of Medicine recommendations on drug safety. N Engl J Med. 2006;355(17):1753-5. Epub 2006 Oct 9. Abstract

Psaty BM, Lumley T, Furberg CD. The metabolic syndrome: time for a critical appraisal: joint statement from the American Diabetes Association and the European Association for the Study of Diabetes: response to Kahn et al. Diabetes Care. 2006;29(1):177;author reply 177-8. Details

Psaty BM, Potter JD. Risks and benefits of celecoxib to prevent recurrent adenomas. N Engl J Med. 2006;355(9):950-2. Details

Psaty BM, Rennie D. Clinical trial investigators and their prescribing patterns: another dimension to the relationship between physician investigators and the pharmaceutical industry. JAMA. 2006;295(23):2787-90. Details

Psaty BM, Weiss NS, Furberg CD. Recent trials in hypertension: compelling science or commercial speech? JAMA. 2006;295(14):1704-6. Details

Shlipak MG, Katz R, Sarnak MJ, Fried LF, Newman AB, Stehman-Breen C, Seliger SL, Kestenbaum B, Psaty B, Tracy RP, Siscovick DS. Cystatin C and prognosis for cardiovascular and kidney outcomes in elderly persons without chronic kidney disease. Ann Intern Med. 2006;145(4):237-46. Abstract

Smith NL, Barzilay JI, Kronmal R, Lumley T, Enquobahrie D, Psaty BM. New-onset diabetes and risk of all-cause and cardiovascular mortality: the Cardiovascular Health Study. Diabetes Care. 2006;29(9):2012-7. Abstract

Smith NL, Heckbert SR, Doggen CJ, Lemaitre RN, Reiner AP, Lumley T, Meijers JC, Psaty BM, Rosendaal FR. The differential association of conjugated equine estrogen and esterified estrogen with activated protein C resistance in postmenopausal women. J Thromb Haemost. 2006;4(8):1701-6. Abstract

Smith NL, Heckbert SR, Lemaitre RN, Reiner AP, Lumley T, Rosendaal FR, Psaty BM. Conjugated equine estrogen, esterified estrogen, prothrombotic variants, and the risk of venous thrombosis in postmenopausal women. Arterioscler Thromb Vasc Biol. 2006;26(12):2807-12. Epub 2006 Sep 14. Abstract

Sotoodehnia N, Siscovick DS, Vatta M, Psaty BM, Tracy RP, Towbin JA, Lemaitre RN, Rea TD, Durda JP, Chang JM, Lumley TS, Kuller LH, Burke GL, Heckbert SR. Beta2-adrenergic receptor genetic variants and risk of sudden cardiac death. Circulation. 2006;113(15):1842-8.  Abstract

2005
Arnold AM, Psaty BM, Kuller LH, Burke GL, Manolio TA, Fried LP, Robbins JA, Kronmal RA. Incidence of cardiovascular disease in older Americans: the Cardiovascular Health Study. J Am Geriatr Soc. 2005;53(2):211-8. Abstract

Cao JJ, Barzilay JI, Peterson D, Manolio TA, Psaty BM, Kuller L, Wexler J, Bleyer AJ, Cushman M. The association of microalbuminuria with clinical cardiovascular disease and subclinical atherosclerosis in the elderly: the Cardiovascular Health Study. Atherosclerosis. 2006;187(2):372-7. Epub 2005 Oct 20. Abstract

Chan JD, Rea TD, Smith NL, Siscovick D, Heckbert SR, Lumley T, Chaves P, Furberg CD, Kuller L, Psaty BM. Association of beta-blocker use with mortality among patients with congestive heart failure in the Cardiovascular Health Study (CHS). Am Heart J. 2005;150(3):464-70. Abstract

Cooper RC, Psaty BM. Should ethnicity serve as the basis for clinical trial design? Diversity and inclusiveness should remain the guiding principles for clinical trials. Circulation. 2005;112(23):3660-5; discussion 3665-6. Details

Cushman M, Arnold AM, Psaty BM, Manokio TA, Kuller LH, Burke GL, Polak JF, Tracy RP. C-reactive protein and the 10-year incidence of coronary heart disease in older men and women: the Cardiovascular Health Study. Circulation. 2005;112(1):25-31. Epub 2005 Jun 27. Abstract

Danesh J, Lewington S, Thompson SG, Lowe GD, Collins R, Kostis JB, Wilson AC, Folsom AR, Wu K, Benderly M, Goldbourt U, Willeit J, Kiechl S, Yarnell JW, Sweetnam PM, Elwood PC, Cushman M, Psaty BM, Tracy RP, Tybjaerg-Hansen A, Haverkate F, de Maat MP, Thompson SG, Fowkes FG, Lee AJ, Smith FB, Salomaa V, Harald K, Rasi R, Vahtera E, Jousilahti P, Pekkanen J, D'Agostino R, Kannel WB, Wilson PW, Tofler G, Arocha-Pinango CL, Rodriguez-Larralde A, Nagy E, Mijares M, Espinosa R, Rodriquez-Roa E, Ryder E, Diez-Ewald MP, Campos G, Fernandez V, Torres E, Coll E, Marchioli R, Valagussa F, Rosengren A, Wilhelmsen L, Lappas G, Eriksson H, Cremer P, Nagel D, Curb JD, Rodriguez B, Yano K, Salonen JT, Nyyssonen K, Tuomainen TP, Hedblad B, Lind P, Loewel H, Koenig W, Meade TW, Cooper JA, De Stavola B, Knottenbelt C, Miller GJ, Cooper JA, Bauer KA, Rosenberg RD, Sato S, Kitamura A, Naito Y, Iso H, Salomaa V, Harald K, Rasi V, Vahtera E, Jousilahti P, Palosuo T, Ducimetiere P, Amouyel P, Arveiler D, Evans AE, Ferrieres J, Juhan-Vague I, Bingham A, Schulte H, Assmann G, Cantin B, Lamarche B, Despres JP, Dagenais GR, Tunstall-Pedoe H, Woodward M, Ben-Shlomo Y, Davey Smith G, Palmieri V, Yeh JL, Meade TW, Rudnicka A, Knottenbelt C, Ridker P, Rodeghiero F, Tosetto A, Shepherd J, Ford I, Robertson M, Brunner E, Shipley M, Feskens EJ, Kromhout D;Fibrinogen Studies Collaboration. Plasma fibrinogen level and the risk of major cardiovascular diseases and nonvascular mortality: an individual participant meta-analysis. JAMA. 2005;294(14):1799-809. Abstract

Diehr P, Johnson LL, Patrick DL, Psaty B. Methods for incorporating death into health-related variables in longitudinal studies. J Clin Epidemiol. 2005;58(11):1115-24. Epub 2005 Sep 12. Abstract

Furberg CD, Psaty BM. Review: Hormone replacement therapy may reduce the risk for death in younger but not older postmenopausal women. ACP Journal Club. 2005;142(1):2. Comment on: Salpeter SR, Walsh JM, Greyber E, Ormiston T, Salpeter EE. Mortality associated with hormone replacement therapy in younger and older women: a meta-analysis. J Gen Intern Med. 2004;19:791-804. ACP Journal Club. 2005;142:1. Also published in Evidence-based Medicine. 2005;10(1):10.Details

Furberg CD, Psaty BM, FitzGerald GA. Parecoxib, valdecoxib, and cardiovascular risk [editorial]. Circulation. 2005;111(3):249. Epub 2005 Jan 17. Details

Glazer NL, Smith NL, Heckbert SR, Doggen CJ, Lemaitre RN, Psaty BM. Risk of myocardial infarction attributable to elevated levels of total cholesterol among hypertensives. Am J Hypertens. 2005;18(6):759-66. Abstract

Hindorff LA, Heckbert SR, Psaty BM, Lumley T, Siscovick DS, Herrington DM, Edwards KL, Tracy RP. Beta-2 adrenergic receptor polymorphisms and determinants of cardiovascular risk: the Cardiovascular Health Study. Am J Hypertens. 2005;18(3):392-7. Abstract

Jackson LA, Nelson JC, Benson P, Neuzil KM, Reid RJ, Psaty BM, Heckbert SR, Larson EB, Weiss NS. Functional status is a confounder of the association of influenza vaccine and risk of all cause mortality in seniors. Int J Epidemiol. 2006;35(2):345-52. Epub 2005 Dec 20. Abstract

Kaplan RC, Tirschwell DL, Longstreth Jr WT, Manolio TA, Heckbert SR, Lefkowitz D, El-Saed A, Psaty BM. Vascular events, mortality, and preventive therapy following ischemic stroke in the elderly. Neurology. 2005;65(6):835-42. Abstract

Psaty BM, Furberg CD. COX-2 inhibitors: lessons in drug safety. N Engl J Med. 2005;352(11):1133-5. Epub 2005 Feb 15. Details

Rautaharju PM, Ge S, Nelson JC, Marino Larsen EK, Psaty BM, Furberg CD, Zhang ZM, Robbins J, Gottdiener JS, Chaves PH. Comparison of mortality risk for electrocardiographic abnormalities in men and women with and without coronary heart disease (from the Cardiovascular Health Study). Am J Cardiol. 2006;97(3):309-15. Epub 2005 Dec 1. Abstract

Rea TD, Breitner JC, Psaty BM, Fitzpatrick AL, Lopez OL, Newman AB, Hazzard WR, Zandi PP, Burke GL, Lyketsos CG, Bernick C, Kuller LH. Statin use and the risk of incident dementia: the Cardiovascular Health Study. Arch Neurol. 2005;62(7):1047-51. Abstract

Reiner AP, Diehr P, Browner WS, Humphries SE, Jenny NS, Cushman M, Tracy RP, Walston J, Lumley T, Newman AB, Kuller LH, Psaty BM. Common promoter polymorphisms of inflammation and thrombosis genes and longevity in older adults: the cardiovascular health study. Atherosclerosis. 2005;181(1):175-83. Epub 2005 Feb 19. Abstract 

Reiner AP, Ziv E, Lind DL, Nievergelt CM, Schork NJ, Cummings SR, Phong A, Burchard EG, Harris TB, Psaty BM, Kwok PY. Population structure, admixture, and aging-related phenotypes in African American adults: the Cardiovascular Health Study. Am J Hum Genet. 2005;76(3):463-77. Epub 2005 Jan 19. Abstract

Sarnak MJ, Katz R, Stehman-Breen CO, Fried LF, Jenny NS, Psaty BM, Newman AB, Siscovick D, Shlipak MG; Cardiovascular Health Study. Cystatin C concentration as a risk factor for heart failure in older adults.. Ann Intern Med. 2005;142(7):497-505. Abstract

Schellenbaum GD, Heckbert SR, Smith NL, Rea TD, Lumley T, Kitzman DW, Roger V, Taylor HA, Psaty BM. Congestive heart failure incidence and prognosis: case identification using central adjudication versus hospital discharge diagnoses. Ann Epidemiol. 2006;16(2):115-22. Epub 2005 Jun 16. Abstract

Schellenbaum GD, Smith NL, Heckbert SR, Lumley T, Rea TD, Furberg CD, Lyles MF, Psaty BM. Weight loss, muscle strength, and angiotensin-converting enzyme inhibitors in older adults with congestive heart failure or hypertension. J Am Geriatr Soc. 2005;53(11):1996-2000. Abstract

Shlipak MG, Fried LF, Cushman M, Manolio TA, Peterson D, Stehman-Breen C, Bleyer A, Newman A, Siscovick D, Psaty B. Cardiovascular mortality risk in chronic kidney disease: comparison of traditional and novel risk factors. JAMA. 2005;293(14):1737-45. Abstract

Shlipak MG, Katz R, Cushman M, Sarnak MJ, Stehman-Breen C, Psaty BM, Siscovick D, Tracy RP, Newman A, Fried L. Cystatin-C and inflammatory markers in the ambulatory elderly. Am J Med. 2005;118(12):1416. Abstract

Shlipak MG, Katz R, Fried LF, Jenny NS, Stehman-Breen CO, Newman AB, Siscovick D, Psaty BM, Sarnak MJ. Cystatin-C and mortality in elderly persons with heart failure. J Am Coll Cardiol. 2005;45(2):268-71. Abstract

Simon GE, Psaty BM, Hrachavec JB, Mora M. Principles for evidence-based drug formulary policy. J Gen Intern Med. 2005;20(10):964-8. Abstract

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