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November 7, 2007

Group Health awarded $23 million for new vaccine research unit
UW and Seattle Children’s Hospital will collaborate in clinical trials

Seattle—The Group Health Center for Health Studies has received a $23.7 million federal contract to establish and lead a Vaccine and Treatment Evaluation Unit (VTEU) that will conduct clinical trials of promising vaccines and therapies for infectious diseases.

Group Health will collaborate with the University of Washington (UW) Department of Medicine, the UW Division of Allergy & Infectious Diseases, and Seattle Children’s Hospital Research Institute to operate the VTEU. The National Institute of Allergy and Infectious Diseases will fund the seven-year contract.

Group Health is now among eight institutions nationwide to host a VTEU, making it an integral part of national efforts to develop safe and effective vaccines for the public good.

“Our strength at recruiting study participants from the Group Health membership is a great advantage for this type of research,” explained Lisa Jackson, MD, MPH, a Group Health senior scientist and the new unit’s principal investigator. “It allows us access to a large and diverse population, which can lead to better evidence about vaccines to protect people of all ages and with a variety of health conditions.” Such knowledge is especially important to respond effectively to emerging public health threats such as pandemic flu and bioterrorism, she added.

The nation’s VTEUs were first established in 1962 as a national resource for vaccine development. VTEU investigators have tested and advanced vaccines for many diseases including influenza, pneumonia, malaria, whooping cough, cytomegalovirus infection, and anthrax.

“Establishing a VTEU in Seattle makes good sense given all the other vaccine research-related activities in our area,” said Willliam J. Bremner, MD, chair of the UW Department of Medicine. He pointed, for example, to UW research on HIV vaccine, biodefense, and emerging infectious diseases, as well as the University’s recent establishment of a Department of Global Health.

Jackson said the unit will also benefit from its scientists’ “strong track record” in vaccine and infectious disease research. The unit’s co-investigators are Dr. Anna Wald, professor in UW’s Department of Medicine and Division of Allergy & Infectious Disease, and Dr. Janet Englund, associate professor of pediatrics in the Department of Infectious Diseases at Seattle Children’s Hospital Research Institute.

The nation’s other VTEUs are located at Baylor College of Medicine in Houston, TX; Children's Hospital Medical Center in Cincinnati, OH; Emory University in Atlanta, GA; the University of Iowa in Iowa City; the University of Maryland at Baltimore; St. Louis University in St. Louis, MO; and Vanderbilt University in Nashville, TN.

About Group Health Center for Health Studies

Founded in 1947, Group Health is a Seattle-based, consumer-governed, nonprofit health care system that coordinates care and coverage. Group Health Center for Health Studies conducts research related to prevention, diagnosis, and treatment of major health problems. It is funded primarily through government and private research grants.

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